Breast Cancer Essay - 992 Words

developing breast cancer, there presence alone does not always result in breast cancer. The two genes that are indicative of breast cancer are BRCA1 and BRCA2. However, these genes are not the only indicators of breast cancer, although, there presence carries the greatest chance of development. The other genes that also serve as indicators of possible breast cancer are CHEK2, PTEN, TP53, PALB2, STK11, and CDH1. These genes are extremely significant because the presence or absence of a mutation form can either prohibit or enable the development of breast cancer. CHEK2 is an abbreviation for checkpoint kinase 2 and is responsible for the creation of a protein that suppresses tumor growth. The presence of this gene being mutated doubles the†¦show more content†¦Peutz-Jeghers syndrome is a genetic disease in which benign tumors develop in the gastrointestinal tract. CDH1 is an abbreviation for Caherin 1 and is a tumor suppressor gene that enables the attachment and organization of cells to form tissues. A mutation in this gene can increase the risk of developing cancer because it can allow a cancer cell to break off and form breast cancer. All these genes proper expression play a large role in prohibiting the growth of tumors. In most cases it is not simply the presence of a mutated form of BRCA1 or BRCA2 that causes the development of breast cancer but a combination of mutated forms of these genes as well. Thus, it is incredibly imperative to not only analyze BRCA1 or BRCA2 but also STK11, CDH1, PALB2, CHEK2, P53 and PTEN as their presence can multiply the chances of an individual developing breast cancer. The ultimate transmission of breast cancer â€Å"interest genes† is not solely based on BRCA1 and BRCA2, but more accurately and often it is the presence of a mutated form of either of those previously listed and the presence of a mutated form of one of many of the tumor suppressors or localizers. A study conducted by Dr. Lineberger of the Unive rsity of North Carolina on the molecular mechanisms of breast cancer progression noted that, â€Å"The development of breast cancer is thought to occur through a multi-step process. The majority of breast cancersShow MoreRelatedMale Breast Cancer Essay861 Words   |  4 Pages Breast cancer in males is quite common, yet still many people are unaware of this disease. Often, it can go undiagnosed until the cancer is in the fourth stage. Every year over 2,000 men will be diagnosed, but only 54% will survive. Cancer in men is often overlooked as it is almost 100 times less common in men than women. 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These glandsRead More Breast Cancer Essay2259 Words   |  10 PagesBreast cancer is the second most common cancer in the world (Breast). Every three minutes a woman is diagnosed: one in eight women will have breast cancer (Walgreens, 2011; Chen, 2010). â€Å"I have to admit, like so many women, I always knew there was a chance. But like so many women, I never thought it would be me. I never thought Id hear those devastating words: You have breast cancer. â€Å"- Debbie Wasserman Schultz, a democratic representative of Florida (2011). Mutations turn genes on and off